Gastronauts

Dr. Gary Schwartz is visiting us on November 5th, 2019

Gary J. Schwartz, Ph.D., is a professor of medicine, neuroscience, and psychiatry at the Albert Einstein College of Medicine. His lab studies how the gut and the brain interact with each other to regulate food intake and associated metabolic processes.  Their research focuses on the sensory neural controls of energy homeostasis in health and disease. They have identified the type of food stimuli that activate vagal and splanchnic sensory fibers supplying the gut, and have revealed the extent to which these stimuli influence gut-brain communication.

Their most recent efforts involve the analysis of gut-brain communication in the control of energy homeostasis in mouse models of obesity and diabetes.We have identified neurons in the periphery, brainstem and hypothalamus that integrate food-elicited signals with peptide signals that have profound effects food intake and metabolism. Data from these studies reveal that central hypothalamic and brainstem neuropeptides affect food intake and body weight by modulating the neural potency of food stimulated signals from the mouth and gut. This novel, synthetic conceptual framework is critical because it links forebrain hypothalamic structures, long known to be involved in the control of energy balance, to the sensory and motor systems in the brainstem that control ingestion, digestion, and metabolic processing of food. Future studies will use genetic mouse models of obesity and diabetes with targeted conditional neuropeptide/ receptor knockdown or replacement to determine how central neuropeptide signaling affects the neural processing of metabolic sensory signals critical to energy homeostasis.

See some of his work here.

JOIN US: NOV 5, 2019 @ 4PM in MSRB3 1125

About

In late 2014, Duke University scientists led by Diego Bohórquez got together to share data and to talk gut-brain science. Little did they know, this meeting would give birth to GASTRONAUTS – a community of researchers passionate about gut-brain matters.

All knowledge comes from people who eat. As such, we are engineers, biologists, neuroscientists, psychiatrists, therapists, patients, science communicators who care about gut-brain matters. From food to mood, we are always thinking about how to tap into the gut to improve human health and the world we live in.

Our mantra is where the gut meets the brain. That mantra has fostered a lively monthly seminar series at Duke University. From September to May, every first Tuesday of the month we gather at 4PM to celebrate knowledge. That mantra has also gone to places. Gastronauts has a biannual symposium. The first of its kind was a special gathering at Duke in 2016 only to be followed by a world class symposium: Gastronauts Singapore 2018. The date for the next experience – Gastronauts Nantes 2020 – is set May 19-21 and the sauce is brewing.

Do you like this intersection? Cheer us on. Would you like to accelerate our research? Funding is the way. Should you find yourself resonating with our mantra, join us. Together we can create knowledge that may enable us to treat diseases of the brain from the gut.

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